1.Heredity and Evolution

 Heredity and Evolution

  • Heredity is the transfer of biological characters from one generation to another via genes. 
  • Gregor Johann Mendel is pioneer of the modern genetics. 
  • In 1901, the reasons behind the sudden changes were understood due to the mutational theory of Hugo de Vries. 
  • Meanwhile in 1902, Walter Sutton observed the paired chromosomes in the cells of grasshopper; until then it was not known to anyone. 
  • Genes are carried via chromosomes. 
  • Through which 1944, trio of scientists Oswald Avery, Mclyn McCarty and Colin McLeod proved that except viruses, all living organisms have DNA as genetic material. 
  • In 1961, the French geneticists Francois Jacob and Jack Monod proposed a model for process of protein synthesis with the help of DNA in bacterial cells. 
  • It helped to uncover the genetic codes hidden in DNA. 
  • The science of heredity is useful for diagnosis, treatment and prevention of hereditary disorders, production of hybrid varieties of animals and plants and in industrial processes in which microbes are used.
Transcription, Translation and Translocation :
  • With the help of RNA, the genes present in the form of DNA participate in the functioning of cell 
  • Information about protein synthesis is stored in the DNA 
  • Proteins are synthesized by DNA through the RNA. This is called as ‘Central Dogma’. 
  • mRNA is produced as per the sequence of nucleotides on DNA. 
  • Only one of the two strands of DNA is used in this process. 
  • The sequence of nucleotides in mRNA being produced is always complementary to the DNA strand used for synthesis. 
  • Besides, there is uracil in RNA instead of thymine of DNA. This process of RNA synthesis is called as ‘transcription
  • The mRNA formed in nucleus comes in cytoplasm. 
  • It brings in the coded message from DNA. The message contains the codes for amino acids. 
  • The code for each amino acid consists of three nucleotides. It is called as ‘triplet codon’. 
  • Dr Har Govind Khorana, a scientist of Indian origin has made an important contribution in discovery of triplet codons for 20 amino acids. 
  • Each mRNA is made up of thousands of triplet codons. 
  • As per the message on mRNA, amino acids are supplied by the tRNA. 
  • For this purpose, tRNA has ‘anticodon’ having complementary sequence to the codon on mRNA. This is called as ‘translation’. 
  • The amino acids brought in by tRNA are bonded together by peptide bonds with the help of rRNA. 
  • During this process, the ribosome keeps on moving from one end of mRNA to other end by the distance of one triplet codon. This is called as ‘translocation’. 
  • Such many chains come together to form complex proteins. 
  • These proteins control various functions in the body of living organisms and their appearance too. 
  • Sometimes, any nucleotide of the gene changes its position that causes a minor change which is nothing but the ‘mutation’. 
  • Ex. Mutation may cause the genetic disorders like sickle cell anaemia.

Evolution  :
  • Evolution is the gradual change occurring in living organisms over a long duration. 
  • Very slow-going process
  • Formation of new species due to changes in specific characters of several generations of living organisms as a response to natural selection, is called as evolution. 
  • 3.5 billion years ago, life had been non existent on the Earth. 
  • Simple elements in the ocean on the Earth and simple type of organic and inorganic compounds may have been formed from those. 
  • Complex compounds like proteins and nucleic acids formed from those simple compounds. 
  • First primitive type of cells may have been formed.
  • Number of those cells may have increased at the cost of surrounding chemicals. 
  • There may had been some differences among those cells and according to the principle of natural selection, some may have shown good growth and some may have perished.
  • At present, crores of species of plants and animals with huge diversity  
  • Organisms are present at all the places like air, water, land, rock, etc. 
  • Different theories about origin and evolution of life have been proposed till today of which theory of 'Gradual development of living organisms is accepted  

Theory of Evolution: 
  • According to this theory, first living material (protoplasm) has been formed in ocean. 
  • In due course of time, unicellular organism was formed. 
  • Larger and more complex organisms were formed. 
  • All those changes were slow and gradual. 
  • Duration of all these changes is at most 300 crore years. 
  • Evolution is organizational. 
  • Progressive development of plants and animals from the ancestors having different structural and functional organization is called evolution.

Evidences of evolution :
1. Morphological Evidences
  • Similarities like structure of mouth, position of eyes, structure of nostrils and ear pinnae and thickly distributed hairs on body are seen in animals 
  • Similarities in characters like leaf shape, leaf venation, leaf petiole, etc. occur in case of plants. 
  • It proves that their origin must be same.
  • Must have common ancestors

2. Anatomical Evidences :
  • There doesn’t seem any superficial similarity between human hand, foreleg of ox, flipper of whale and patagium of bat. 
  • There is similarity in structure of bones and joints in organs of each of those animals. 
  • This similarity indicates that those animals may have common ancestor.
3. Vestigial Organs:
  • Degenerated or underdeveloped useless organs of organisms are called as vestigial organs. 
  • Organ, though non-functional in certain organisms, it may be functional in other organisms i.e. it is not vestigial in other organisms. 
  • Appendix, which is useless to human, is useful and fully functional organ in ruminants. 
  • Similarly, muscles of ear pinna, which are useless to human, are useful in monkeys for movement of ear pinna. 
  •  Various vestigial organs like tail-bone (coccyx), wisdom teeth, and body hairs are present in body of human being
4. Palaeontological Evidences:
  • Large number of organisms get buried due to disasters like flood, earthquake, volcano, etc. 
  • Remnants and impressions of such organisms remain preserved underground. These are called as fossils. 
  • Study of fossils is an important aspect of study of evolution.
  • In case of dead bodies of plants and animals, instead of remaining constant, the ratio between C-14 and C-12 changes continuously as C-12 is non-radioactive. 
  • The time passed since the death of a plant or animal can be calculated by measuring the radioactivity of C-14 and ratio of C-14 to C-12 present in their body. This is ‘carbon dating’ method. 
  • It is used in palaeontology and anthropology for determining the age of human fossils and manuscripts. 
  • Once the age of fossil been determined by such technique, it becomes easy to deduce the information about other erstwhile organisms. 
  • It seems that vertebrates have been slowly originated from invertebrates.

Introduction to Scientists :
  • Carbon dating method is developed by Willard Libby. 
  • He has been awarded with Nobel Prize (1960) for this invention. 
  • The age of the materials determined by this method are published in the journal ‘Radio Carbon’
5. Connecting Links :
  • Some plants and animals show some morphological characters by which they can be related to two different groups; hence they are called as ‘connecting links’. 
  •  Ex. In Peripatus, characters like segmented body, thin cuticle, and parapodia-like organs are present. Similarly, these animals show tracheal respiration and open circulatory system similar to arthropods. 
  • This indicates that Peripatus is connecting link between annelida and arthropoda. 
  •  Similarly, duck billed platypus lays eggs like reptiles but shows relationship with mammals too due to presence of mammary glands and hairs. 
  • Lung fish performs respiration with lungs irrespective of being fish. 
  • Mammals are evolved from reptiles and amphibians from fishes.

6. Embryological Evidences: 
  • All embryos show extreme similarities during initial stages and those similarities decrease gradually. 
  • Similarities in initial stages indicate the common origin of all these animals. 

Darwin’s theory of natural selection :
  • Published the theory of natural selection which preaches the survival of fittest. 
  • Published a book titled ‘Origin of Species’. 
  • Darwin says that all the organisms reproduce prolifically. 
  • All the organisms compete with each other in a life--threatening manner. 
  • Sustaining and selected organisms can perform reproduction and thereby give rise to the new species with their own specific characters. 
  • Darwin’s theory of natural selection was widely accepted for long duration. 
Objections were raised against the theory. 
  1. Natural selection is not the only factor responsible for evolution. 
  2. Darwin did not mention any explanation about useful and useless modifications. 
  3. There is no explanation about slow changes and abrupt changes.

Introduction to Scientists : Charles Robert Darwin 
  • Proposed the theory of evolution. 
  • Showed that all the species of living organisms have been gradually evolved over the period of thousands of years from common ancestor. 
  • Proposed that principle of natural selection is responsible for this evolution.

Lamarckism Jean-Baptiste :
  • Lamarck proposed that morphological changes occurring in living organisms are responsible for evolution and the reason behind those morphological changes is activities or laziness of that organism. 
  • He called this concept as principle of ‘use or disuse of organs’. 
  • Acquired characters’  are transferred from one to another generation. This is called as theory of inheritance of acquired characters or Lamarckism
  • Development of organs due to specific activities or their degeneration due to no use at all was widely accepted but transfer of those characters from generation to generation was rejected. 
  • Modifications brought in us are not transferred to next generation and thereby Lamarck’s theory was disproved. 
  •  The living organism can transfer the characters which it has acquired, to the next generation. This is called ancestry of acquired characters

Introduction to Scientists
Jean-Baptiste Lamarck  
  • Proposed that the activities of the organisms are responsible for their evolution. 
  • Proposed that each animal or plant undergo some changes in its life span and those changes are transferred to the next generation and such changes occur in next subsequent generations too.
Speciation :
  • Formation of new species of plants and animals is the effect of evolution. 
  • Species is the group of organisms that can produce fertile individuals through natural reproduction. 
  • Genetic variation is responsible for formation of new species from earlier one. 
  • Besides, geographical and reproductive changes are also responsible. 
  • Similarly, geographical or reproductive isolation also leads to speciation 

Human Evolution :
  • The biodiversity that is known today has been said to be formed from very simple unicellular organism due to evolution. 
  • Last dinosaurs disappeared approximately seven crore years ago. 
  • Tail of monkey-like animals of Africa is said to be disappeared about 4 crore years ago. 
  • They developed due to enlargement in brain their hands were also improved and thus ape-like animals were evolved. 
  • Meanwhile, these ape-like animals reached the South and North-East Asia and finally evolved into gibbon and orang-utan.
  • Remaining ape-like animals stayed in Africa and from them, gorilla and chimpanzee evolved about 2.5 crore years ago. 
  • Evolution of some of the 2 crore year old species of apes -  use their hands more for eating food and other work. 
  • First human--like animals with erect posture which were using their hands have evolved about 2 crore years ago.
  • First record of human-like animal is with us in the form of ‘Ramapithecus’ ape from North India and East Africa. 
  • Afterwards, this ape grown up in size and became more intelligent and thus the ape of South Africa evolved about 40 lakh years ago.
  • The morphology of these human-like animals started to appear like to be the member of the genus Homo, about 20 lakh years ago and thus skilled human developed. 
  • About 15 lakh years ago, human walking with erect posture was evolved. It may have existed in China and Indonesia of Asian continent.
  • Evolution of upright man - about 1 lakh years and meanwhile it discovered the fire. 
  • Brain of 50 thousand year old man had been sufficiently evolved to the extent that it could be considered as member of the class- wise-man (Homo sapiens). 
  • Neanderthal man can be considered as the first example of wise-man. 
  • The Cro-Magnon man evolved about 50 thousand years ago and afterwards, this evolution had been faster than the earlier
  • About 10 thousand years ago, wise-man started to practice the agriculture. 
  • Art of writing was invented about 5000 years ago.
  • Modern sciences emerged about 400 years ago 
  • Industrial society was established about 200 years ago.